اثرات ریفامپین و کلوگزاسیلین بر روی حاملین بینی استافیلوکوک طلائی در بیمارستان حضرت رسول اکرم(ص)

45 health personnels who were nasal carriers of staph aureus entered in this trial, seven subjects were omitted for various reesos, remainders randomly divided to 3 groups and were treated orally for 4 days. - group I with rifampin & cloxacilline - group 1/ with rifampin & placebo - group 11/ with cloxacilline & placebo All subjects were recultured 3 ~eeks after the completion of treatment. In group I, all 14 subjects were culture negative (100% cure), in group 1/10 out of 14 were culture negative (71% cure) and, in group 11/5 out of 10 (50%), were cultur negative. K.K statistical analysis method gave a P<0.017. For comparison of three groups mamm-whitny test was used that yeilded following results: - difference between group I & 1/ (P<0.033)29% - difference between group I & II/(P< 0.036) 50% - difference between group 1/ & 11/ (P<0.29)29% In conclusion, oral use of rifampin and cloxacilline for four days is a suitable combination for treatment of staph aureus carriers. *(comparision between the use of rifampin and cloxacillin alone was not possible due to low number of subjects)